The relationship between race, genetics, and health is very complex. Genetics refers to our human genome, and the blueprint from which humans are made. All people share the same genetic code and have the same genes, however, there are variations within these genes that make us unique from one another. Genes are directly related to health because variations in a gene can make one more or less likely to develop a disease or be prone to mutation. For example, if an individual has one normal copy and one mutated copy of the gene for sickle cell, they are considered heterozygous and will express a resistance to the disease Malaria. However, if an individual is homozygous and receives two mutated copies of the gene, it can cause full symptom sickle cell anemia and be very detrimental to ones health. Race, however, is not as clear-cut. Race is determined by how an individual identifies him or herself and has no biological basis. Often race is determined by skin color but different ethnicities can identify with the same race. Because race is subjectively determined, race is not directly related to health.
Cystic fibrosis (CF) is one of the most commonly inherited genetic disorders among Caucasians. It is caused by the lack of a protein that controls the balance of chloride in the body, and causes the body to produce thick, sticky mucus. This causes recurrent lung infections and breathing difficulties and can also involve problems with reproduction and digestion. Cystic fibrosis is an autosomal recessive condition which means that an individual must have two mutated versions of the CFTR gene, one from each parent. If an individual has no working copies of the gene, they will not be able to make the gene product and cystic fibrosis will develop, with the symptoms ranging from mild to very severe.
Cystic fibrosis does however protect against diseases such as cholera and typhoid, which were common in Europe many years ago. Having the mutation in the CFTR gene offered protection from these diseases and the mutated gene may have been selected for among the Caucasian population. This could maybe explain why cystic fibrosis is most common in Caucasians today.
Cystic Fibrosis Foundation. “About Cystic Fibrosis.” Lat modified in 2014. http://www.cff.org/aboutcf/